IVIG (Intra Venous Immune Gobulin) is used to treat a variety of autoimmune, infectious, and idiopathic diseases. Depending on your specific case, infusion can last from four to six hours. The US Food and Drug Administration has approved the use of IVIG for primary immunodeficiencies, immune-mediated thrombocytopenia, Kawasaki disease, hematopoietic stem cell transplantation in patients older than 20 years (Gamimune-N only), chronic B-cell lymphocytic leukemia, and pediatric HIV type 1 infection. IVIG also has many off-label uses. Common side effects include headache, fatigue, and rash. Your doctor should discuss other rare but potentially serious side effects and potential drug interactions with you prior to treatment.